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phenobarbital will lessen the level or result of diazepam buccal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. Robust or average CYP3A4 inducers could raise price of diazepam elimination; thus, efficacy of diazepam can be decreased.Watch Carefully (1)phenobarbital will minimize the level or impact of tofacitinib by